Leukocyte telomere length associated with glioma risk and survival
نویسندگان
چکیده
منابع مشابه
Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk.
Telomere maintenance has emerged as an important molecular feature with impacts on adult glioma susceptibility and prognosis. Whether longer or shorter leukocyte telomere length (LTL) is associated with glioma risk remains elusive and is often confounded by the effects of age and patient treatment. We sought to determine if genotypically-estimated LTL is associated with glioma risk and if inher...
متن کاملIs Leukocyte Telomere Length Related with Lung Cancer Risk?: A Meta-Analysis
Background: Epidemiological studies have probed the correlation between telomere length and the risk of lung cancer, but their findings are inconsistent in this regard. The present meta-analysis study has been carried out to demonstrate the association between relative telomere length in peripheral blood leukocytes and the risk of lung cancer using an established Q-PCR technique. Methods:...
متن کاملAssociation between leukocyte telomere length and glioma risk: a case-control study.
BACKGROUND Compelling epidemiological evidence indicates that alterations of telomere length are associated with risks of many malignancies in a tumor-specific manner, such as lung cancer, breast cancer, and non-Hodgkin's lymphoma. However, the association between leukocyte telomere length and glioma risk has not been investigated. METHODS Relative telomere length (RTL) of peripheral blood le...
متن کاملChildhood Obesity Is Associated with Shorter Leukocyte Telomere Length
CONTEXT Obesity in adults is associated with shorter mean leukocyte telomere length (LTL), a marker of biological age that is also associated with age-related conditions including cardiovascular disease and type 2 diabetes. However, studies of childhood obesity and LTL have proved inconclusive. OBJECTIVE The objective of the study was to clarify the relationship between telomere length and ch...
متن کاملLeukocyte telomere length is associated with measures of subclinical atherosclerosis.
AIMS Our aim was to test the association of mean leukocyte telomere length (LTL) with ultrasonic measures of subclinical atherosclerosis such as intima-media thickness in the common carotid (IMTcc) and sum of plaque areas (SPA) and with serological markers. METHODS AND RESULTS Carotid and femoral bifurcations were scanned in 762 general population volunteers (46% men) over 40. Four features w...
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ژورنال
عنوان ژورنال: Aging and Cancer
سال: 2020
ISSN: 2643-8909,2643-8909
DOI: 10.1002/aac2.12020